Institute of Nutritional Endocrinology (INE): Organic Acid Testing – Part 7: Amino Acid Markers and Phosphoric Acid

Organic Acid Testing
Part 7 – Amino Acid Markers and Phosphoric Acid

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#1. Significant increase in this amino acid metabolite is due to a reduced ability to metabolize the amino acid leucine.
#2. Phosphate urinary excretion is directly proportional to dietary intake.
#3. Elevations in this marker result from intake of phenylalinine, genetic carrier status for PKU, or from a deficiency in production of biopterin.
#4. A significant increase in branch chained amino acid metabolites is associated with MSUD (Maple Syrup Urine Disease).
#5. Low urinary phosphate occurs in low intake and in vitamin D excess.

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